Our Team

Administration

Rudolph L. Juliano, Ph.D.

Boshamer Distinguished Professor And Associate Dean For Research And Graduate Education At The UNC E

Rudy Juliano is the Boshamer Distinguished Professor and Associate Dean for Research and Graduate Education at the UNC Eshelman School of Pharmacy. In addition to leading our project on Nanopatterned Surfaces for Tumor Cell Analysis, he currently serves as the Principal Investigator for a Program Project grant from the NIGMS focused on understanding the biodistribution and pharmacodynamics of genes and oligonucleotides. He has served on the faculty of the University of Toronto, the University of Texas Medical School at Houston, and the School of Medicine, University of North Carolina, where he was Chair of the Dept. of Pharmacology for 16 years. His research interests include cell adhesion proteins, signal transduction, drug delivery systems, and the molecular therapeutics of cancer. He was involved in some of the earliest work using lipid nanoparticles (liposomes) as drug delivery agents for therapy of infectious diseases and cancer, including development of a formulation of liposomal amphotericin B that is currently used in the clinic. He has served on numerous NIH study sections as well as the editorial boards of Cancer Research, Pharmaceutical Research, Biochimica et Biophysica Acta, Journal of Drug Targeting, Oligonucleotides, Molecular Pharmacology, Advanced Drug Delivery Reviews, and the Journal of Cell Biology.

Juliano obtained his Ph.D. in Biophysics at the University of Rochester and followed with postdoctoral work in Experimental Pathology at Roswell Park Memorial Institute.

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Joseph DeSimone, Ph.D.

Chancellor's Eminent Professor Of Chemistry

Joseph DeSimone is the Chancellor’s Eminent Professor of Chemistry at the University of North Carolina at Chapel Hill and William R. Kenan Jr. Professor of Chemical Engineering at North Carolina State University. DeSimone is the director of UNC’s Institute for Advanced Materials, Nanoscience and Technology, director of the emerging Institute for Nanomedicine at UNC, and leads our projects using Top-down Nanofabrication Techniques Applied to the Design of Engineered Drug Therapies. In 2005, DeSimone was elected into the National Academy of Engineering and the American Academy of Arts and Sciences. DeSimone has received 37 major awards and recognitions including the Lemelson-MIT Prize for Invention and Innovation, and was named the 2008 Tar Heel of the Year by the Raleigh News and Observer. Among DeSimone’s notable inventions is an environmentally friendly manufacturing process that relies on supercritical carbon dioxide for the creation of fluoropolymers or high-performance plastics and development of a novel drug-eluting stent, which is now being evaluated in an international clinical trial for the treatment of coronary artery disease. DeSimone recently launched Liquidia Technologies (www.liquidia.com) which is focused on providing enhanced delivery mechanisms for therapeutics.

DeSimone obtained his Ph.D. in Chemistry at Virginia Tech, and subsequently joined the faculty at UNC-Chapel Hill. DeSimone has published over 240 scientific articles and has over 115 issued patents in his name with over 70 patents pending.

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Susan Wohler Sunnarborg, Ph.D.

Associate Director

Dr. Sunnarborg is an Associate Professor in the Department of Biochemistry and Biophysics, where she studies the developmental and pathophysiological roles of the EGF family of growth factors, and their zinc metalloprotease-regulated shedding. She is the scientific and administrative contact for the C-CCNE and manages day-to-day operations, seminars, symposia and community outreach efforts.

A graduate of the University of Michigan, she obtained her Ph.D. in Biochemistry, Molecular Biology and Biophysics at the University of Minnesota before joining the Postdoctoral Training Program at the UNC Lineberger Comprehensive Cancer Center.

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Project Leaders

Joseph DeSimone, Ph.D.

Chancellor's Eminent Professor Of Chemistry

Joseph DeSimone is the Chancellor’s Eminent Professor of Chemistry at the University of North Carolina at Chapel Hill and William R. Kenan Jr. Professor of Chemical Engineering at North Carolina State University. DeSimone is the director of UNC’s Institute for Advanced Materials, Nanoscience and Technology, director of the emerging Institute for Nanomedicine at UNC, and leads our projects using Top-down Nanofabrication Techniques Applied to the Design of Engineered Drug Therapies. In 2005, DeSimone was elected into the National Academy of Engineering and the American Academy of Arts and Sciences. DeSimone has received 37 major awards and recognitions including the Lemelson-MIT Prize for Invention and Innovation, and was named the 2008 Tar Heel of the Year by the Raleigh News and Observer. Among DeSimone’s notable inventions is an environmentally friendly manufacturing process that relies on supercritical carbon dioxide for the creation of fluoropolymers or high-performance plastics and development of a novel drug-eluting stent, which is now being evaluated in an international clinical trial for the treatment of coronary artery disease. DeSimone recently launched Liquidia Technologies (www.liquidia.com) which is focused on providing enhanced delivery mechanisms for therapeutics.

DeSimone obtained his Ph.D. in Chemistry at Virginia Tech, and subsequently joined the faculty at UNC-Chapel Hill. DeSimone has published over 240 scientific articles and has over 115 issued patents in his name with over 70 patents pending.

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Otto Zhou, Ph.D.

David Godschalk Professor Of Physics And Materials Sciences

Zhou is the David Godschalk Professor of Physics and Materials Sciences and a member of the UNC Lineberger Comprehensive Cancer Center. He holds over 50 issued/pending U.S. patents in the areas of nanotechnology and has published extensively in this area. He is also the co-founder and Chairman of Xintek and a board director of XinRay System which is a joint venture of Siemens and Xintek. He received his PhD degree in Materials Science from the University of Pennsylvania and worked at Bell Labs and NEC before joining the faculty at UNC.

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Wenbin Lin, Ph.D.

Professor Of Chemistry

Dr. Wenbin Lin is Professor of Chemistry and Molecular Pharmaceutics at the University of North Carolina at Chapel Hill. His research focuses on designing novel supramolecular systems and hybrid nanomaterials for applications in chemical and life sciences. Dr. Lin has been the recipient of National Science Foundation CAREER Award (1999), an Arnold and Mabel Beckman Young Investigator Award (2000), a Research Corporation Cottrell Scholar Award (2000), an Alfred P. Sloan Research Fellowship (2000), and a Camille Dreyfus Teacher-Scholar Award (2001). He has authored or co-authored more than 150 papers in several different research areas. He received his BS degree in chemical physics from University of Science and Technology of China in Hefei in 1988, and his Ph.D. degree in Chemistry from University of Illinois at Urbana-Champaign in 1994.

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J. Michael Ramsey, Ph.D.

Minnie N. Goldby Distinguished Professor Of Chemistry

J. Michael Ramsey is the Goldby Distinguished Professor of Chemistry at the University of North Carolina at Chapel Hill. In addition to his appointment in the Department of Chemistry, he is also a member of the faculty in the Department of Biomedical Engineering and the Carolina Center for Genome Sciences in the UNC-CH School of Medicine and a member of the Institute of Advanced Materials, Nanoscience, and Technology. His research focuses on the development of micro- and nanofluidic devices for the elucidation of biological information. Specific efforts include technology development for the study of cell signal transduction and protein expression at the single cell level, structural characterization of single DNA molecules, artificial ion channel devices for intra-cellular chemical sensing, and the development of point-of-care clinical diagnostic devices. Dr. Ramsey is a Fellow of the Optical Society of America and the American Institute for Medical and Biological Engineering. He is also a recipient of a senior Alexander von Humboldt Award, the Frederick Capillary Electrophoresis Award, the A. J. P. Martin Gold Medal for Separation Science, the Marcel J.E. Golay Award in Capillary Chromatography, the Jacob Heskel Gabbay Award in Biotechnology and Medicine, the American Chemical Society Division of Analytical Chemistry Award in Chemical Instrumentation, the Pittsburgh Analytical Chemistry Award and the American Chemical Society Award in Chromatography. In addition, he is the scientific founder of Caliper Life Sciences, Corp., the leading supplier of commercial Lab-on-a-Chip products. Ramsey received his Ph.D. in chemistry from Indiana University.

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Research Project

Rudolph L. Juliano, Ph.D.

Boshamer Distinguished Professor And Associate Dean For Research And Graduate Education At The UNC E

Rudy Juliano is the Boshamer Distinguished Professor and Associate Dean for Research and Graduate Education at the UNC Eshelman School of Pharmacy. In addition to leading our project on Nanopatterned Surfaces for Tumor Cell Analysis, he currently serves as the Principal Investigator for a Program Project grant from the NIGMS focused on understanding the biodistribution and pharmacodynamics of genes and oligonucleotides. He has served on the faculty of the University of Toronto, the University of Texas Medical School at Houston, and the School of Medicine, University of North Carolina, where he was Chair of the Dept. of Pharmacology for 16 years. His research interests include cell adhesion proteins, signal transduction, drug delivery systems, and the molecular therapeutics of cancer. He was involved in some of the earliest work using lipid nanoparticles (liposomes) as drug delivery agents for therapy of infectious diseases and cancer, including development of a formulation of liposomal amphotericin B that is currently used in the clinic. He has served on numerous NIH study sections as well as the editorial boards of Cancer Research, Pharmaceutical Research, Biochimica et Biophysica Acta, Journal of Drug Targeting, Oligonucleotides, Molecular Pharmacology, Advanced Drug Delivery Reviews, and the Journal of Cell Biology.

Juliano obtained his Ph.D. in Biophysics at the University of Rochester and followed with postdoctoral work in Experimental Pathology at Roswell Park Memorial Institute.

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Website
Research Project